Jianguo Ji;Chih-Hung Lee;Tao Li;Murali Gopalakrishnan;Kevin B. Sippy
发明人:
Murali Gopalakrishnan,Chih-Hung Lee,Jianguo Ji,Tao Li,Kevin B. Sippy
申请号:
US12787937
公开号:
US09040568B2
申请日:
2010.05.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
This invention discloses a method of treatment of osteoarthritis pain by administration of a composition containing a nicotinic acetylcholine receptor ligand and a nicotinic acetylcholine receptor subtype α4β2 allosteric modulator. The present application also relates to compositions comprising such compounds for use in treating pain and related disorders mediated by controlling neurotransmitter release in a subject.