LONDON HEALTH SCIENCES CENTRE RESEARCH INC.;REGENTS OF THE UNIVERSITY OF MINNESOTA
发明人:
TURLEY, EVA,MCCARTHY, JIM,TOLG, CORNELIA,LUYT, LEONARD G.
申请号:
CA2702366
公开号:
CA2702366C
申请日:
2008.10.10
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Compositions comprising hyaluronic acid (HA) or agents that interfere with HAbinding of HA receptors andmethods of using the same are provided. For example, there is provided acomposition comprising HA oligomers ranging in size from10-mer to 80-mer and use of the same for promoting migration, growth orsurvival of wild-type or transformed/cancerous cells.There is also provided a composition comprising an agent that interferes withbinding between an HA oligomer of a size of about10-mer to about 80-mer and an HA receptor. Such compositions may be useful fortherapeutic, diagnostic or imaging applications.Examples of therapeutic use are wound repair or cancer treatment.