KRISTI A. LEONARD,KENT BARBAY,JAMES P. EDWARDS,KEVIN D. KREUTTER,DAVID A. KUMMER,UMAR MAHAROOF,RACHEL NISHIMURA,MAUD URBANSKI,HARIHARAN VENKATESAN,AIHUA WANG,RONALD, L. WOLIN,CRAIG R. WOODS,JOAN PIERC
申请号:
PT13786564
公开号:
PT2909192T
申请日:
2013.10.15
申请国别(地区):
PT
年份:
2017
代理人:
摘要:
The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.