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Antibody production method
专利权人:
中外製薬株式会社
发明人:
山田 良樹,喜安 達也,田畑 和之,葛巻 章浩,山城 舞
申请号:
JP2009538093
公开号:
JP4976502B2
申请日:
2008.10.14
申请国别(地区):
JP
年份:
2012
代理人:
摘要:
The present invention provides a method of producing a recombinant antibody efficiently and at low cost. Disclosed is a method of producing an antibody or a fragment thereof, comprising allowing a cell to produce the antibody or the fragment, wherein the cell contains a larger number of copies of an exogenous DNA encoding the light chain or a fragment thereof of the antibody than the number of copies contained in the cell of an exogenous DNA encoding the heavy chain or a fragment thereof of the antibody. The present invention also provides a recombinant vector comprising one copy of a DNA encoding the heavy chain or a fragment thereof of an antibody and two or more copies of a DNA encoding the light chain or a fragment thereof of the antibody; and a transformant.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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