The present disclosure relates to endoscopic reposable surgical clip appliers having a shaft assembly. The shaft assembly includes a spindle, pusher bar, and a barrel assembly. The spindle and pusher bar are each translatably supported within the shaft assembly. The barrel cam assembly includes a first portion in mechanical communication with the spindle and a second portion in mechanical communication with the pusher bar. Translation of the spindle effectuates rotation of a portion of the barrel cam assembly and the rotation of the portion of the barrel cam assembly effectuates translation of the pusher bar.