ENZYMES DE REPARATION DE L'ADN CIBLANT LE NOYAU ET PROCEDES D'UTILISATION

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专利权人:

OREGON HEALTH & SCIENCE UNIVERSITY

发明人:

LLOYD. R. STEPHEN,MCCULLOUGH, AMANDA

申请号：

CA3080179

公开号：

CA3080179A1

申请日:

2018.11.14

申请国别(地区):

CA

年份:

2019

代理人:

摘要：

The present disclosure provides polypeptides that have the ability to repair DNA damage by recognizing and removing a wide variety of DNA damage and distortions in double-stranded DNA. In particular, the polypeptides have the ability to remove cyclobutane pyrimidine dimers (CPDs) and/or (6-4) photoproducts from DNA. The polypeptides include at least one heterologous targeting sequence.

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