NUCLEAR-TARGETED DNA REPAIR ENZYMES AND METHODS OF USE

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专利权人:

Oregon Health &； Science University

发明人:

R. Stephen Lloyd,Amanda K. McCullough

申请号：

US16762852

公开号：

US20200283745A1

申请日:

2018.11.14

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present disclosure provides polypeptides that have the ability to repair DNA damage by recognizing and removing a wide variety of DNA damage and distortions in double-stranded DNA. In particular, the polypeptides have the ability to remove cyclobutane pyrimidine dimers (CPDs) and/or (6-4) photoproducts from DNA. The polypeptides include at least one heterologous targeting sequence.

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中国工程科技知识中心

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http://www.ckcest.cn/home/