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Espiroindolina derivatives as antagonists of gonadotropin-releasing Hormone Receptor
专利权人:
BAYER INTELLECTUAL PROPERTY GMBH
发明人:
PANKNIN, OLAF,BÄURLE, STEFAN,RING, SVEN,SCHWEDE, WOLFGANG,BONE, WILHELM,NOWAK-REPPEL, KATRIN,BENDER, ECKHARD,NUBBEMEYER, REINHARD,GNOTH, MARK, JEAN
申请号:
CR20140343
公开号:
CR20140343A
申请日:
2014.07.16
申请国别(地区):
CR
年份:
2014
代理人:
摘要:
Spiroindoline derivatives, process for their preparation and pharmaceutical compositions thereof, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially sex-hormone-related diseases in both men and women, in particularly those selected from the group of endometriosis, uterine fibroids, polycystic ovarian disease, hirsutism, precocious puberty, gonadal steroid-dependent neoplasia such as cancers of the prostate, breast and ovary, gonadotrope pituitary adenomas, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hypertrophy, contraception and infertility (e.g., assisted reproductive therapy such as in vitro fertilization). The present application relates in particular to spiroindoline derivatives as gonadotropin-releasing hormone (GnRH) receptor antagonists.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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