A method of operating a glucose management device. The glucose management device includes one or more processing components, a housing, a user interface including a display and a user-input mechanism, and a memory. The method includes displaying on the display a prompt for initiating a carbohydrate factor determination sequence via the user-input mechanism and displaying on the display at least one query, the at least one query including a query associated with a user's type of diabetes. The method further includes receiving the user's response to the at least one query via the user-input mechanism and determining, via the at least one processing component, the carbohydrate factor using the user's response to the at least one query and information stored in the memory.