Itching therapeutic agent

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专利权人:

CHUGAI SEIYAKU KABUSHIKI KAISHA

发明人:

YOSHINOBU HIGUCHI,KEIKO KASUTANI,HIDETOMO KITAMURA,MASAKAZU HASEGAWA

申请号：

BRPI0821145

公开号：

BRPI0821145A2

申请日:

2008.12.05

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The present inventors isolated clone BM095 from a human antibody phage library, which had a strong growth inhibitory activity in the IL-31-dependent Ba/F3 cell growth assay system. When administered to pruritus model mice, the anti-mouse NR10 neutralizing antibody exhibited a marked symptom-suppressing effect. Thus, it was revealed that anti-NR10 neutralizing antibodies are useful as therapeutic agents for pruritus.

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中国工程科技知识中心

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