Therapeutic agent for pruritus

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专利权人:

Chugai Seiyaku Kabushiki Kaisha

发明人:

Kasutani, Keiko,Hasegawa, Masakazu,Kitamura, Hidetomo,Higuchi, Yoshinobu

申请号：

AU2008332276

公开号：

AU2008332276B2

申请日:

2008.12.05

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

A clone BM095 having a potent proliferation-inhibiting activity is obtained from a human antibody phage library in an IL-31-dependent Ba/Fc cell proliferation assay system. When the anti-mouse NR10 neutralizing antibody is administered to a pruritus model mouse, a significant effect of preventing the conditions of the disease is observed. It is revealed that the anti-NR10 neutralizing antibody is useful as a therapeutic agent for pruritus.

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