A device for disinfecting catheter connectors comprising a container (2) having a closed lower base end (2b) and an opposite open upper end (2a) and a sponge-like element (3) inserted inside the container (2), impregnated with a liquid medical substance (4). The sponge-like element (3) has an axial through cavity (5) within it and a semi-rigid insert (6) housed in the cavity (5).
