JONES, Frank, R.,BALINT, Joseph,RICE, Adrian,LATCHMAN, Yvette,GABITZSCH, Elizabeth
申请号:
EP17828593
公开号:
EP3484509A4
申请日:
2017.07.14
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
Compositions of a recombinant adenovirus based vector vaccine containing one or more flavivirus antigen genes are disclosed herein. Methods for constructing and producing such vaccines and methods of using these vaccines to generate immune responses against flaviviruses are also described. Compositions described herein allow for vaccinations in subjects with preexisting immunity to adenovirus.