Jan Kehler,Jacob Nielsen,Mauro Marigo,John Paul Kilburn,Morten Langgård
申请号:
US14016685
公开号:
US08796304B2
申请日:
2013.09.03
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention is directed to compounds with the structurewhich are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.