SVENSTRUP, Niels,SIMONSEN, Klaus Baek,RASMUSSEN, Lars Kyhn,JUHL, Karsten,LANGGARD, Morten,WEN, Kate,WANG, Yazhou
申请号:
AU2017200886
公开号:
AU2017200886B2
申请日:
2017.02.09
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2017200886B220180118.pdf#####PDE9 INHIBITORS WITH IMIDAZO TRIAZINONE BACKBONE ABSTRACT This invention is directed to compounds, which are PDE9 enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula (I). The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula (I). The present invention further provides a compound of formula (I) for use in a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject ta therapeutically effective amount of a compound of formula (I).