PEPTIDES CYCLIQUES COMPRENANT AU MOINS UN RESIDU AZA-BETA-3 AMINOACYCLE ET LEURS UTILISATIONS

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专利权人:

Centre National de la Recherche Scientifique

发明人:

LAURENCIN, Mathieu,ZATYLNY-GAUDIN, Céline,HENRY, Joël,BAUDY FLOCH, Michèle

申请号：

EP08867746.3

公开号：

EP2197899B8

申请日:

2008.10.08

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

Cyclic peptides having a random alternation of L-alpha -aminoacyl residues and aza-beta 3>-aminoacyl residues (A), are new. Cyclic peptides having a random alternation of L-alpha -aminoacyl residues and aza-beta 3>-aminoacyl residues of formula (-NH-N(R 1)-CH 2-C(=O)-) (A), are new. R 1lateral chain comprising proteogenic or non-proteogenic group. Provided that, two L-alpha -aminoacyl residues are separated by at least one aza-beta 3>-aminoacyl residues and total number of L-alpha -aminoacyl residues and aza-beta 3>-aminoacyl residues is 4-8. ACTIVITY : Antimicrobial Antibacterial Antiparasitic Virucide Fungicide Antitubercular Tuberculostatic Immunosuppressive Antiinflammatory Respiratory-Gen. MECHANISM OF ACTION : None given.

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