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ORAL PHARMACEUTICAL COMPOSITION COMPRISING TASTE-MASKED N-ACETYLCYSTEINE
专利权人:
Hermes Arzneimittel GmbH
发明人:
BECKER KARIN,BECKER KARIN,HAACK DETLEV,HAACK DETLEV,SALAR BEHZADI SHARAREH,SALAR BEHZADI SHARAREH,ZIMMER ANDREAS,ZIMMER ANDREAS
申请号:
PL14716609
公开号:
PL2983650T3
申请日:
2014.04.11
申请国别(地区):
PL
年份:
2017
代理人:
摘要:
The invention provides coated particles with taste-masked N-acetylcysteine. The particles comprise a core with the active ingredient and a coating comprising a triglyceride and a surfactant. The particles exhibit rapid drug release and a stable release profile. Moreover, the invention provides a hot-melt coating method for manufacturing such particles, and pharmaceutical compositions comprising the particles. The method allows the coating of core particles at moderate temperatures, thereby preventing the degradation of the thermolabile active ingredient.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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