Kamal Chowdhury;Shashi Kumar Gupta;Thomas Thum;Ahmet Ucar
发明人:
Thomas Thum,Kamal Chowdhury,Ahmet Ucar,Shashi Kumar Gupta
申请号：
US14342867
公开号：
US09388411B2
申请日:
2012.09.06
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention refers to inhibitors of microRNAs, particularly of microRNAs miR-212 and/or miR-132 for use in medicine, particularly in the diagnosis, treatment or prevention of cardiac disorders, e.g. cardiac hypertrophy-associated or autophagic disorders, and further refers to isolated nucleic acid molecules, particularly microRNAs miR-212 and/or miR-132 and related sequences, for use in medicine, particularly human medicine, more particularly in the diagnosis, treatment or prevention of disorders involving cardiac atrophy and/or dysfunctional autophagy, e.g. cardiac cachexia.
