Medizinische Hochschule Hannover;Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.
发明人:
申请号:
EP12758827.5
公开号:
EP2753696B1
申请日:
2012.09.06
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention refers to inhibitors of microRNAs, particularly of microRNAs miR-212 and/or miR-132 for use in medicine, particularly in the diagnosis, treatment or prevention of cardiac disorders, e.g. cardiac hypertrophy-associated or autophagic disorders, and further refers to isolated nucleic acid molecules, particularly microRNAs miR-212 and/or miR-132 and related sequences, for use in medicine, particularly human medicine, more particularly in the diagnosis, treatment or prevention of disorders involving cardiac atrophy and/or dysfunctional autophagy, e.g. cardiac cachexia.