Described is a novel, new, inexpensive approach to screen, perform early diagnosis (on asymptomatic and symptomatic subjects for example), diagnose, establish root causes, and treat subjects. A series of medical steps, each of which is designed to provide the administering healthcare provider with both subjective and objective risk, health and cause evaluation information provides a guide a practitioner to treatments that prevent, slow, delay, stop, or reverse the chronic disease conditions at the root of their cause. Each step in the process provides intelligence about cause and effect. The sum of the steps, when evaluated based on patient outcome, is the basis of a chronic disease health learning engine that leads to continuous improvement of medical knowledge, disease, and methods of healing and treatments to improve patient outcomes.