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Amino substituted imidazopyridazines
专利权人:
Bayer Intellectual Property GmbH
发明人:
EIS, Knut,PÜHLER, Florian,ZORN, Ludwig,SCHOLZ, Arne,LIENAU, Philip,GNOTH, Mark,BÖMER, Ulf,GÜNTHER, Judith,HITCHCOCK, Marion
申请号:
ES12761564
公开号:
ES2638319T3
申请日:
2012.09.05
申请国别(地区):
ES
年份:
2017
代理人:
摘要:
A compound of general formula (I): ** Formula ** in which: R1 represents a linear C2-C6 alkyl group, a linear C1-C6 alkyl-O-linear C1-C6 alkyl, a branched C3-C6 alkyl, a C3-C6 cycloalkyl, a linear C1-C6 alkyl-C3-C6 cycloalkyl or a C3-C6 cycloalkyl-linear C1-C6 alkyl which is optionally substituted, one or more times, independently of one another, with a substituent selected from: a halogen atom, a -CN group, C1-C6 alkyl, C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C10 cycloalkyl optionally connected as a spiro, a 3 to 10 membered heterocycloalkyl which is optionally connected as spiro, aryl, aryl that is optionally substituted one or more times independently of each other with R, heteroaryl, heteroaryl that is optionally substituted one or more times independently of each other with R, -C (>; = O) NH2, -C ( >; = O) N (H) R ', -C (>; = O) N (R') R '', -C (>; = O) OH, - C (>; = O) O'R, -NH2, -NHR ', -N (R') R '', -N (H) C (>; = O) R ', -N ( R ') C (>; = O) R', -N (H) S (>; = O) R ', -N (R') S (>; = O) R ', - N (H) S (>; = O) 2R ', -N (R') S (>; = O) 2R ', -N>; = S (>; = O) (R') R '', -OH, C1-C6 alkoxy, C1-C6 haloalkoxy , -OC (>; = O) R ', -OC (>; = O) NH2, -OC (>; = O) NHR', -OC (>; = O) N (R ') R' ', -SH, alkyl C1-C6-S-, -S (>; = O) R ', -S (>; = O) 2R', -S (>; = O) 2NH2, -S (>; = O) 2NHR ', - S (>; = O) 2N (R ') R' '; ** Formula ** represents a group: ** Formula ** in which * indicates the point of union of said group with the rest of the molecule; and R3 represents a substituent selected from: a halogen atom, a group -CN, C1-C6 alkyl, C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 alkynyl, - C (>; = O) R ', -C (>; = O) NH2, -C (>; = O) N (H) R ', -C (>; = O) N (R') R '', -NH2, -NHR ', -N (R') R '', -N (H) C (>; = O) R ', -N (R') C (>; = O) R ', - N (H) C (>; = O) NH2, -N (H ) C (>; = O) NHR ', -N (H) C (>; = O) N (R') R '', -N (R ') C (>; = O) NH2, -N (R') C (>; = O) NHR ', - N (R') C (>; = O) N (R ')
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