A kind of method, it is used to prepare a conveying drug delivery system, drug, it has one or more active medicine mixtures, its water solubility having less than 1 g in 30 ml water and nano-diamond, include the following steps: that dissolving active medicine mixture enters the nonaqueous solvents at a two poles of the earth to form one first mixture, one of deionized water surfactant is dissolved in form a surfactant solution, it adds multiple nano-diamond particles and spreads nano-diamond particle in the surfactant solution for therefore forming a Nano diamond dispersion to surfactant solution, first mixture is added to disperse to nano-diamond, stir dispersion simultaneously to form one second mixture Dry second mixture is to produce the dry mash as a drug delivery system.
