NOVEL METHODS FOR PROVIDING LONG-TERM PROTECTIVE IMMUNITY AGAINST RABIES IN ANIMALS, BASED UPON ADMINISTRATION OF REPLICATION-DEFICIENT FLAVIVIRUS EXPRESSING RABIES G
The present invention relates to compositions comprising replication defective chimeric flavivirus anti-rabies vaccines, methods of producing the vaccines, and the administration of such vaccines to companion animals, including dogs. The invention further relates to methods for providing long-term protective immunity against rabies in companion animals, including dogs and cats.La présente invention concerne des compositions comprenant des vaccins antirabiques à base de flavivirus chimérique défectueux en termes de réplication, des procédés de production des vaccins et ladministration de tels vaccins à des animaux de compagnie, comprenant les chiens. Linvention concerne en outre des procédés de fourniture dune immunité de protection à long terme contre la rage chez des animaux de compagnie, comprenant les chiens et les chats.