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2-piperidin-1-yl-acetamide compounds for use as tankyrase inhibitors
专利权人:
Atwood Kim Cheung
发明人:
Atwood Kim Cheung,Donovan Noel Chin,Jianmei Fan,Karen Marie Miller-Moslin,Michael David Shultz,Troy D Smith,Ronald Charles Tomlinson,Bakary-Barry Toure,Michael Scott Visser,Zhuoliang Chen
申请号:
US14154161
公开号:
US09181266B2
申请日:
2012.07.13
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides for compounds of formula (I):wherein R1-R5 and L are defined herein. The present invention also provides for pharmaceutical compositions and combinations comprising a compound of formula (I) as well as for the use of such compounds as tankyrase inhibitors and in the treatment of Wnt signaling and tankyrase 1 and 2 signaling related disorders which include, but are not limited to, cancer.
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