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transdermally absorbable preparation
专利权人:
Teikoku Seiyaku Co.; Ltd.
发明人:
ITO, Takeshi,ISHIGURE, Miho
申请号:
ES09726157
公开号:
ES2672025T3
申请日:
2009.03.25
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
A transdermally absorbable preparation (1) comprising a laminate (6) comprising, in order from the skin contact side, an outer membrane (3), a drug-containing layer (4), and a support layer ( 5); said external membrane that is intended to be in contact with the skin, fixing means (7) for fixing said laminate (6) on the skin, comprising, in order from the side in contact with the skin, an adhesive layer (10 ) and a covering layer (9), and covers said laminate, and an internal layer (12) having an internal hole (13), is provided between said support layer (5) and said adhesive layer (10) and is extends outwards from the peripheral region of said support layer (5); wherein said outer membrane (3) is a drug-permeable polymeric membrane having drug-permeable pores, ensures controlled release of the drug into the skin, and is provided on the skin contact surface, and wherein said inner layer (12) and said support layer (5) comprise a drug impervious material, and in which said adhesive layer (10) is directly contacted with one side of said support layer (5) through said internal hole (13) of said internal layer (12) and fixes said laminate (6), and in which said internal layer (12) is capable of separating said adhesive layer (10) and the lateral side of said layer containing the drug (4) during the application of said transdermally absorbable preparation (1).Una preparación absorbible transdérmicamente (1) que comprende un laminado (6) que comprende, en orden desde el lado en contacto con la piel, una membrana externa (3), una capa que contiene el fármaco (4) y una capa de soporte (5); dicha membrana externa que está destinada a estar en contacto con la piel, medios de fijación (7) para fijar dicho laminado (6) sobre la piel, que comprende, en orden desde el lado en contacto con la piel, una capa adhesiva (10) y una capa de cobertura (9), y cubre dicho laminado, y una capa interna (12) que tiene un orificio interno (13), se proporciona entre dicha capa de soporte (5) y d
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