Brandenburg, Boerries,Vogels, Ronald,Kolkman, Joost A.,Friesen, Robert Heinz Edward
申请号：
AU2016214304
公开号：
AU2016214304A1
申请日:
2016.02.05
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The present invention relates to monomeric and multimeric binding molecules that are capable of specifically binding to hemagglutinin (HA) of at least two influenza A virus strains, said strains comprising HA of two different HA subtypes from phylogenetic group 2； or capable of specifically binding to hemagglutinin (HA) of at least one influenza A virus strain from phylogenetic group 1 and at least one influenza A virus strain from phylogenetic group 2； or capable of specifically binding to hemagglutinin (HA) of at least one influenza B virus strain. The binding molecules preferably are also capable of neutralizing at least two influenza A virus strains from phylogenetic group 2； or capable of neutralizing at least one influenza A virus strain from phylogenetic group 1 and at least one influenza A virus strain from phylogenetic group 2； or capable of specifically neutralizing at least one influenza B virus strain.
