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Biochemistry specificity dual transmembrane antibody
专利权人:
CHIANG; CHIH-TA
发明人:
CHIANG, CHIH TA,江支达,江支達
申请号:
TW103127664
公开号:
TW201605890A
申请日:
2014.08.13
申请国别(地区):
TW
年份:
2016
代理人:
摘要:
Immunology is a modern specialized academic field, which deals with how a cell outer membrane surface antigen elicits an immune response through the antibody and thus plays an important role in eliminating epidemic by effectively treating the disease, yet it has a limitation for being unable to enter a cell body, and this is exactly the shortcoming that the transmembrane antibody can overcome by entering a cell body to produce an immune response. The generation of dual transmembrane antibody must overcome the different characteristics between the cell outer membrane and organelles inner membrane in order to allow vaccine antibody to enter into the cell organelle membrane, and combine with the specificity antigen of pathogen body to produce an immune response. Broadly speaking, the dual transmembrane antibody is able to get across two extracellular envelopes when microorganisms invade a cell body, the dual transmembrane antibody can enter into the microorganism body of the invading cells, and react with antigens in the microorganism body to generate immune response, so as to paralyze the microorganisms in order to treat the disease. Narrowly defined, the dual transmembrane antibody can enter into membrane-containing organelles of a cell body to elicit an immunization effect. In short, when there is mutation or disease inside a membrane-containing organelle, the dual transmembrane antibody can enter inside the diseased or mutated organelle, thus triggering an immune response for disabling the antigen, so as to paralyze the diseased cell.免疫學是現代一門專門的學問,細胞外膜表面抗原經由抗體引發免疫反應,是免除疫情的要角,其作用是治療疾病,其限制是無法進入細胞體內,而跨膜抗體正可以彌補缺點,進入細胞體內產生免疫反應,然而雙跨膜抗體的產生,係克服細胞外膜與胞器內膜之差異特性,使得疫苗抗體進入細胞胞器膜中,與病源本體之特異性抗原結合產生免疫反應,雙跨膜抗體廣義而言係跨過兩個細胞外被膜,當微生物侵入細胞體內,使用雙跨膜抗體,既可進入入侵細胞之微生物體內,與微生物體內抗原發生免疫反應,進而癱瘓微生物,以治療該疾病。狹義而言雙跨膜抗體更可進入細胞體內有胞膜之胞器中進行免疫作用,簡言之當有胞膜之胞器內部發生變異或病變時,既可利用雙跨膜抗體進入病變變異之胞器內部,引發免疫反應,使抗原失能,進而癱瘓該病變細胞。圖2-1→圖2-2→圖2-3為正常細胞分裂簡式,圖2-2→圖2-4→圖2-5→2-6為細胞受到前置誘發產生基因變型,再由雙頭端分裂開始,經過基因重組,最後產生四條基因片斷,在癌化過程圖中足以得知:1.具有共同演
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中国工程科技知识中心
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