Stabilized human immunodeficiency virus 'hiv' env elope 'env' trimer vaccines and methods of using same

• 收藏
• 分享

专利权人:

BETH ISRAEL DEACONESS MEDICAL CENTER INC

发明人:

NKOLOLA JOSEPH,BAROUCH DAN H

申请号：

AP201508634

公开号：

AP201508634A0

申请日:

2014.01.07

申请国别(地区):

AP

年份:

2015

代理人:

摘要：

The invention features isolated human immunodeficiency virus (HIV) envelope (Env) trimers, in which the amino acid sequence of the Env polypeptides is optimized to stabilize formation of the trimers. The invention also features vaccines, nucleic acids, and vectors to deliver and/or facilitate production of the stabilized HIV Env trimers. In addition, the invention features methods of making and using the stabilized HIV Env trimers of the invention.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/