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Systems with espiroesteroidales Neuroactive and anti-inflammatory effects
专利权人:
CENTRO DE INVESTIGACION Y DESARROLLO DE MEDICAMENTOS
发明人:
YAMILA VERDECIA REYES,ESTAEL OCHOA RODRIGUEZ,LAURA GARCIA PUPO,YANIER NUEZ FIGUEREDO,JUAN ENRIQUE TACORONTE MORALES
申请号:
ARP120105012
公开号:
AR089491A1
申请日:
2012.12.27
申请国别(地区):
AR
年份:
2014
代理人:
摘要:
These molecular entities have anti glucose and anti-inflammatory effects and can be used to treat chronic and acute inflammation, neurodegeneration, neuropsychology and neurology. Requirement 1: a helix cholesterol system with nerve activity and anti-inflammatory effect, composed of nitrogen dioxide, hexachlorobenzene, Solana and the combined helix ring in its structure, used in medicine, belonging to the general formula group (1),(2)(3) And (4) in all natural forms and forms, for general formula compounds (1),(2)(3) And (4),R1,R2 and r83088 represent h, hydroxy, ethyl, propyl, butyl, pentachlorobenzene, hydroxy, propoxy, propoxy, alkane, alquenoiloxi and alcoxicarboniloxi (preferably the tar group of eight linear or branched carbon atoms, and all the above chain isomers);R1,R2 and r830808 also represent an Amin group, which is usually replaced by rented communities, diaklamino, alquenilaminos, diacquenilaminos, aminoboniloxi, pitch and diaquinilamino. The tar group usually has up to eight linear or separable carbon atoms, such as methyl, ethyl, propyl, butyl, pentachlorobenzene, hexilo, hetilo and octimo, and all the above chain isomers; R1,R2 and r83088 also represent amido, sulfur, sulfur, sulfate and sulfur. The sulfur group is best replaced by rental, alkane, alquenoiloxiaris and alquenilla groups. The tar group usually has up to eight linear or separable carbon atoms, such as methyl, ethyl, propyl, butyl, pentachlorobenzene, hexilo, hetilo and octimo, and all the above chain isomers; R1,R2 and r83088 also represent cyanogens, thiocyanes and isothiocyanes, which are replaced by tar, azidoalquilos, alcoiloxielquilos, arilalquilos, heteromorphic love, arilalquenilos, heteromorphic love, arilalquinilos, arilalquinilos, alcoiloxiarilalquinilos and isomerization groups, Therefore, cyanopropyl substitutes can be replaced by isoacrylonitrile, oxyalkene, alcoxunil, calcium carbamate and aclominoquinil. The tar group usually has up to 8 linear or branched carbon atoms,
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