Christopher G. Salentine,Kieran O'Donoghue,Kieran ODonoghue
申请号:
US12381467
公开号:
US08815953B2
申请日:
2009.03.12
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides topical formulations containing a vitamin K analog, e.g., menadione, that deliver a uniform, therapeutically effective concentration of the vitamin K analog to the skin in a vehicle which is stable, non-irritating, non-drying and cosmetically acceptable. These topical formulations are useful for the treatment and prevention of dermatological conditions associated with inflammation, particularly, dermatological conditions resulting from anti-EGFR therapies.