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FORMULATIONS OF VITAMIN K ANALOGS FOR TOPICAL USE
专利权人:
Spectrum Pharmaceuticals; Inc.
发明人:
Christopher G. Salentine,Kieran O'Donoghue,Kieran ODonoghue
申请号:
US14336876
公开号:
US20140336268A1
申请日:
2014.07.21
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides topical formulations containing a vitamin K analog, e.g., menadione, that deliver a uniform, therapeutically effective concentration of the vitamin K analog to the skin in a vehicle which is stable, non-irritating, non-drying and cosmetically acceptable. These topical formulations are useful for the treatment and prevention of dermatological conditions associated with inflammation, particularly, dermatological conditions resulting from anti-EGFR therapies.
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