NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY
发明人:
SHIMIZU MASAO,清水 政男
申请号：
JP2011000068
公开号：
JP2012140380A
申请日:
2011.01.04
申请国别(地区):
JP
年份:
2012
代理人:
摘要：
PROBLEM TO BE SOLVED: To provide a method of producing 2-alkoxy-substituted benzoxathiin compound which is safe and convenient.SOLUTION: The 2-alkoxy-substituted benzoxathiin compound represented by a general formula (A) is produced by reacting a thiosalicylic acid compound represented by a general formula (B) with an orthoformic acid ester compound, in the presence of an acid. In the general formula (A), a substituent R1 presents a group or an atom selected from 1-8C chain alkyl group, 3-8C cyclic alkyl group, 1-8C alkoxyl group and halogen atom. When there are a plurality of R1s, the respective R1s may be equal to each other or may be different from each other, and n is an integer of 0 or 1 to 4. R2 presents a 1-6C alkyl group. In the general formula (B), a substituent R1 presents a group or an atom selected from 1-8C chain alkyl group, 3-8C cyclic alkyl group, 1-8C alkoxyl group, 2-12C alkoxycarbonyl group and phenyl group and halogen atom. When there are a plurality of R1s, the respective R1s may be equal to each other or may be different from each other, and n is an integer of 0 or 1 to 4.COPYRIGHT: (C)2012,JPO&INPIT【課題】安全で簡便な2-アルコキシ置換ベンゾオキサチイン化合物の製造方法の提供。【解決手段】酸の存在下に一般式(B)で表されるチオサリチル酸化合物とオルトギ酸エステル化合物を反応させて一般式(A)で表される2-アルコキシ置換ベンゾオキサチイン化合物を製造する。【選択図】なし
