FORMULATION LIQUIDE STABLE DE L'ANTICORPS ANTI-CD20 OFATUMUMAB

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专利权人:

GLAXOSMITHKLINE LLC

发明人:

BRISBANE, CHARLENE E.,KETKAR, AMOL SHARAD,LASHMAR, ULLA TOVE

申请号：

CA2692681

公开号：

CA2692681C

申请日:

2008.07.03

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The invention relates to an ofatumumab formulation comprising ofatumumab, 50mMsodium acetate, 51 mM chloride, 1% arginite free base, 0.05 mM EDTA and 0.02%polysorbate 80, with the formulation having a pH of 5.5. In addition toimproving stability,the formulation also prevents aggregation of the antibody.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/