СУИННИ Келли Энн (US),ХЕРТЕР Патрисия Нелл (US),НЭДИГ Дэвид Е. (US),СМИТ Дэвид (US),ТОМАС Вэнс Хайден (US),ВОРМЕН Мартин Пол (US)
申请号：
RU2016122882
公开号：
RU2016122882A
申请日:
2014.10.31
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
Processes of preparing pharmaceutical compositions comprising 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1) in Form I and a solid dispersion comprising substantially amorphous N-(5-hydroxy-2,4-ditert-butyl-phenyl)-4-oxo-1H-quinoline-3-carboxamide (Compound 2), methods of treating, lessening the severity of or symptomatically treating CFTR mediated diseases, such as cystic fibrosis, methods of administering, and kits thereof are disclosed.
