SUBSTITUTED INHIBITORS OF MENIN-MLL AND METHODS OF USE

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专利权人:

Inc.;Kura Oncology

发明人:

Tao WU,Liansheng LI,Pingda REN

申请号：

US16647855

公开号：

US20200216471A1

申请日:

2018.09.19

申请国别(地区):

US

年份:

2020

代理人:

摘要：

The present disclosure provides methods of inhibiting the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins. The methods are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin. Compositions for use in these methods are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/