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MULTIVALENT AND MULTIEPITOPIC ANTIBODIES HAVING AGONISTIC ACTIVITY AND METHODS OF USE
专利权人:
Genentech; Inc.
发明人:
Greg LAZAR,Yanli YANG,Erin H. CHRISTENSEN,Julie HANG,Jeong KIM,Seth HARRIS
申请号:
US15669861
公开号:
US20180057598A1
申请日:
2017.08.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Provided herein are tetravalent antigen binding complexes having agonist activity for a cell surface receptor. In some embodiments, the complexes comprise binding specificities for multiple epitopes of the same cell surface receptor. Further provided herein are nucleic acids, vectors, host cells, pharmaceutical compositions, and methods of production related thereto.
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