Tissue manipulation during ocular surgery may be achieved by a variety of systems and techniques. In particular implementations, a system may include spaced apart levers, hinge members, a grasping mechanism, and a guide mechanism located between the levers. A first hinge member may extend from one of the levers to the guide mechanism and move the guide mechanism in one of a proximal or distal direction when the levers are moved toward each other. The grasping mechanism may be coupled to the guide mechanism and extend distally from the guide mechanism. A second hinge member may extend from one of the levers and be coupled to a tube that surrounds a portion of the grasping mechanism. The second hinge member distally displaces the tube when the levers are moved towards each other. The relative motion of the guide mechanism and the tube may cause actuation of the grasping mechanism.眼睛手術期間之組織操控,可經由各種系統以及技術達到。在特別的實施中,系統可包括間隔開之操縱桿、鉸鏈元件、抓取機構以及位在該等操縱桿之間之導向機構。第一鉸鏈元件可從該等操縱桿之一延伸至該導向機構,且在當該等操縱桿朝彼此移動時,於近端或遠端方向之一上移動該導向機構。該抓取機構可連結至該導向機構,且從該導向機構向遠端延伸。第二鉸鏈元件可從該等操縱桿之一延伸出來,連結至環繞該抓取機構之一部分之管子。當該操縱桿朝彼此移動時,該第二鉸鏈元件會將該管子向遠端推移。該導向機構以及該管子之相對移動,可引起該抓取機構之作動。100‧‧‧系統、儀器110a、110b‧‧‧操縱桿112‧‧‧終端120‧‧‧抓取機構122‧‧‧導件124a、124b‧‧‧抓取手臂130‧‧‧管子133、131‧‧‧箭頭140‧‧‧鉸鏈總成142a、142b‧‧‧前鉸鏈元件144a、144b‧‧‧後鉸鏈元件150‧‧‧櫬套160‧‧‧導向機構170‧‧‧元件