Tissue manipulation during ocular surgery may be achieved by a variety of systems and techniques. In particular implementations, a system may include spaced apart levers, hinge members, a grasping mechanism, and a guide mechanism located between the levers. A first hinge member may extend from one of the levers to the guide mechanism and move the guide mechanism in one of a proximal or distal direction when the levers are moved toward each other. The grasping mechanism may be coupled to the guide mechanism and extend distally from the guide mechanism. A second hinge member may extend from one of the levers and be coupled to a tube that surrounds a portion of the grasping mechanism. The second hinge member distally displaces the tube when the levers are moved towards each other. The relative motion of the guide mechanism and the tube may cause actuation of the grasping mechanism.