ANTICORPS CONTRE IL33R HUMAIN ET SES UTILISATIONS

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专利权人:

F. HOFFMANN-LA ROCHE AG

发明人:

FERTIG, GEORG,GEORGES, GUY,KALUZA, KLAUS,LIFKE, VALERIA,MOELLEKEN, JOERG,OFFNER, SONJA,PASHINE, ACHAL,SEEBER, STEFAN,FISCHER, JENS

申请号：

CA2824500

公开号：

CA2824500A1

申请日:

2012.02.22

申请国别(地区):

CA

年份:

2012

代理人:

摘要：

An antibody binding to IL33R characterized in that the heavy chain variable domain comprises a CDR3 region of SEQ ID NO: l, a CDR2 region of SEQ ID NO:2 and a CDRl region of SEQ ID NO:3 and in that the light chain variable domain comprises a CDR3 region of SEQ ID NO:4, a CDR2 region of SEQ ID NO:5 and a CDRl region of SEQ ID NO:6 or a a chimeric, humanized or T cell epitope depleted antibody variant thereof has advantageous properties for the treatment of inflammatory diseases.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/