USE OF RAD18 INHIBITORS IN THE TREATMENT OF TUMORS

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专利权人:

Centre National De La Recherche Scientifique

发明人:

Domenico Maiorano

申请号：

US15536437

公开号：

US20170362593A1

申请日:

2015.12.21

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention relates to the use of an inhibitor of Rad18 expression or activity, in treating a tumor or in sensitizing a patient affected with a tumor, to a treatment with an antineoplastic agent that is a DNA damaging chemotherapeutic agent so to both reduce the self renewal of cancer stem cells and increase the DNA damage response thus boosting apoptotic cell death.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/