COMPOSÉS TRICYCLIQUES FUSIONNÉS POUR LE TRAITEMENT DE TROUBLES INFLAMMATOIRES

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专利权人:

MERCK SHARP & DOHME CORP.

发明人:

申请号：

EP10838138.5

公开号：

EP2512238B1

申请日:

2010.12.09

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention relates to certain lactam ring-containing compounds of the Formula (I) and pharmaceutically acceptable salts thereof, wherein D, E, X1, R1, R2, R3, R4, R9, and R10 are as herein described. In addition, the invention relates to pharmaceutically acceptable compositions comprising at least one such compound, and methods of using the compounds for treating or preventing various inflammatory disorders such as rheumatoid arthritis, inflammatory bowel disease, psoriasis, asthma, and chronic obstructive pulmonary disorder.

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