A hollow fiber membrane type blood purification device that filled the hollow fiber membrane consisting of polyvinyl pyrrolidone and polysulfone-based resin, it is possible to suppress the decrease in blood compatibility elution of polyvinylpyrrolidone is small and can be irradiated sterilized with radiation, It is an object of the present invention is to provide a hollow fiber membrane type blood purification device having excellent handling properties lightweight called semi-dry. Hollow fiber membrane bundle consisting of polyvinyl pyrrolidone and polysulfone-based resin is filled into a container, forming the hollow fiber membrane outer chamber and a hollow fiber membrane inner chamber held by the potting material between the container and the bundle end, the hollow fiber membrane A hollow fiber membrane type blood purification device having a fluid inlet and outlet leading to the hollow fiber membrane outer chamber and the fluid inlet and outlet leading to the inner chamber, the hollow fiber membrane 80% adhesion rate of radical trapping material to the dry weight of the hollow fiber membrane 300% or less, water content is less than 100% of 40% or more, to provide a hollow fiber membrane type blood purification device is characterized in that it is radiation sterilized.ポリスルホン系樹脂とポリビニルピロリドンからなる中空糸膜を充填した中空糸膜型血液浄化装置であって、放射線で照射滅菌してもポリビニルピロリドンの溶出が少なく、かつ血液適合性の低下をも抑制できる、セミドライと呼ばれる軽量で取扱性に優れた中空糸膜型血液浄化装置を提供することを課題とする。ポリスルホン系樹脂とポリビニルピロリドンからなる中空糸膜束が容器に充填され、束端と容器との間をポッティング剤によって保持されて中空糸膜内側室と中空糸膜外側室を形成し、中空糸膜内側室に通じる流体出入口および中空糸膜外側室に通じる流体出入口を持つ中空糸膜型血液浄化装置であって、該中空糸膜は中空糸膜の乾燥重量に対するラジカルトラップ材料の付着率が80%以上300以下%、水分率が40%以上100%未満であり、放射線滅菌されていることを特徴とする中空糸膜型血液浄化装置を提供する。