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New compositions of fat-soluble substances
专利权人:
DSM IP ASSETS B.V.
发明人:
FUNDA, Elger
申请号:
ES05768966
公开号:
ES2587016T3
申请日:
2005.08.01
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
Compositions comprising a) a matrix substance that forms an external (continuous) phase; and b) an internal (discontinuous) phase within said matrix substance, which comprises b1) a fat-soluble physiologically active ingredient that is embedded in b2) a physiologically acceptable encapsulating substance that is solid at room temperature and that, together with said physiologically active ingredient liposoluble, is homogeneously soluble in an organic solvent, which is selected from the group consisting of isopropanol, hexane, cyclohexane, acetone, methyl ethyl ketone, methylene chloride, chloroform, toluene, tetrahydrofuran, ethyl ester of acetic acid, where The fat-soluble physiologically active ingredient is a carotenoid, wherein the encapsulating substance is a wax and wherein said composition is prepared by the steps of dissolving the fat-soluble physiologically active ingredient and the encapsulating substance in a common organic solvent for both substances to obtain a phase. oil, emulsify the oil phase with a solution aqueous ion of the matrix substance, evaporate the organic solvent and, if desired, convert the emulsion into a solid state composition.Composiciones que comprenden a) una sustancia de matriz que forma una fase externa (continua); y b) una fase interna (discontinua) dentro de dicha sustancia de matriz, que comprende b1) un ingrediente fisiológicamente activo liposoluble que está embebido en b2) una sustancia encapsulante fisiológicamente aceptable que es sólida a temperatura ambiente y que, junto con dicho ingrediente fisiológicamente activo liposoluble, es homogéneamente soluble en un disolvente orgánico, que se selecciona del grupo que consiste en isopropanol, hexano, ciclohexano, acetona, metil-etil-cetona, cloruro de metileno, cloroformo, tolueno, tetrahidrofurano, éster etílico del ácido acético, en donde el ingrediente fisiológicamente activo liposoluble es un carotenoide, en donde la sustancia encapsulante es una cera y en donde dicha compo
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