FIELD: medicine, pharmaceutics.SUBSTANCE: present invention refers to organic chemistry, namely to new imidazolidin-2,4-dione derivatives of general formula in the form of racemates, enantiomers or any combinations thereof, or to pharmaceutically acceptable salts thereof, wherein R1 and R2 independently represent alkyls, halogenalkyls, cyano-, nitro-, amino-, -NR8-CO-R5, -NR8-SO2-R5, -NR8-CO-(CH2)n-NR6R7, -NR8-SO2-(CH2)n-NR6R7 or -CO-NH2 n is specified in 0 and 1 R5 represents alkyl R6 and R7 independently represent hydrogen atoms, alkyls and alkyloxycarbonyls R8 represents a hydrogen atom or alkyl R3 represents alkyl, or two radicals R3 together with a carbon atom whereto attached form cycloalkyl containing 4 members R4 represents halogenalkyl containing 4 to 6 carbon atoms Y represents a linear or branched alkylene containing 5 to 11 carbon atoms alkylene may be substituted or may contain two additional members -O- X represents -S-, -SO, -SO2-, -S=N(R)- or -S(O)=N(R9)- R9 represents a hydrogen atom or halogenalkylcarbonyl. Also, the invention refers to the specific compounds of formula (I), to a method for preparing the compound of formula (I) if X = S, to intermediate compounds, to a pharmaceutical composition of the compound of formula (I) and using the compound of formula (I).EFFECT: there are prepared new imidazolidin-2,4-dione derivatives possessing antiproliferative activity.21 cl, 4 dwg, 47 exНастоящее изобретение относится к области органической химии, а именно к новым производным имидазолидин-2,4-диона общей формулы (I) в форме рацематов, энантиомеров или любых комбинаций этих форм, или к их фармацевтически приемлемым солям, где R1 и R2 независимо представляют собой алкилы, галогеналкилы, циано-, нитро-, амино-, -NR8-CO-R5, -NR8-SO2-R5, -NR8-CO-(CH2)n-NR6R7, -NR8-SO2-(CH2)n-NR6R7 или -CO-NH2 n выбран из 0 и 1 R5 представляет собой алкил R6 и R7 независимо представляют собой атомы водорода, алкилы или алкилоксикарбонилы R8 представляет собой атом водорода
