Murphy, Michael Patrick,Smith, Robin Andrew James,Hartley, Richard Charles
申请号：
AU2014351802
公开号：
AU2014351802A1
申请日:
2014.11.21
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
The invention relates to compounds having Formula (1): A-L-B or pharmaceutically acceptable salts thereof, wherein: A is a dicarbonyl sequestering moiety comprising a substituted aryl group or a substituted heteroaryl group； L is an optional linker moiety； and B is a mitochondrial targeting moiety. The invention also relates to pharmaceutical compositions containing such compounds and salts, and to the use of such compounds and salts for treating diabetes, preferably hyperglycaemic diabetes. A mass spectrometry probe and to a method of labelling a biological molecule 1 for mass spectrometry detection are also described.
