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BMP-2 upregulating compounds for healing bone tissue and screening methods for selecting such compounds
专利权人:
Southwest Research Institute
发明人:
Jorge Gianny Rossini
申请号:
US13896993
公开号:
US09216181B2
申请日:
2013.05.17
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present disclosure relates to a method to stimulate endogenous BMP-2 up-regulation in a subject which method comprises administering to a subject an effective amount of an H1 receptor antagonist, whereby endogenous BMP-2 up-regulation is stimulated in said subject. Also provided is a pharmaceutical formulation including an H1 receptor antagonist present in an effective amount to stimulate BMP-2 up-regulation in a subject and a kit.
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