George N. Pavlakis;John N. Vournakis;Barbara K. Felber;Sergio Finkielsztein
发明人:
George N. Pavlakis,John N. Vournakis,Barbara K. Felber,Sergio Finkielsztein
申请号:
US12666052
公开号:
US09931377B2
申请日:
2008.06.27
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to agents that modulate interleukin-15 (“IL-15”) signal transduction or function (“Therapeutic Agents”) and the use ol″ those agents to modulate immune function. The Therapeutic Agents target the interaction between IL-15 and its receptor and modulate IL-15-induced signal transduction. The Therapeutic Agents may be formulated with polymers, such as poly-β-1-♦4-N-acetylglucosamine. for administration to a human subject to modulate IL-15-mediated immune function.