FAZIONI STEFANO,LIVI VALERIA,SIVIERO LUIGI,MCKENNON MARC,SPOONEMORE HOLLY,HOVDA KEITH
申请号:
IN3150/KOLNP/2009
公开号:
IN269584B
申请日:
2009.09.04
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The invention relates to a method for determining the amount of conjugated taxane, in particular paclitaxel, in a PGA-taxane conjugate said method comprising: a) reacting the PGA-taxane conjugate with a compound formula (I): R1 R2N-NH2 (I). wherein R1 and R2 are as defined in the description to give a unbound taxane and a PGA hydrazide and b) determinin the amount of unbound taxane.