The present invention relates to aminopropoxyphenyl and benzyl 1-oxa-4,9-diazaspiroundecane derivatives having dual pharmacological activity towards both the α2δ subunit, in particular the α2δ-1 subunit, of the voltage-gated calcium channel and the µ-opioid receptor, to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy, in particular for the treatment of pain.本發明係關於對電壓閘控鈣通道之α2δ亞單位、特別是α2δ-1亞單位及µ-類鴉片受體具有雙重藥理學活性的胺基丙氧基苯基及苯甲基1-氧雜-4,9-二氮雜螺十一烷衍生物、製備該等化合物之方法、包含其之醫藥組合物，以及其在療法、特別是用於治療疼痛的用途。
