Vladimir Malinin,Walter Perkins,Franziska Leifer,Donna M. Omiatek,Jane Ong,Renu Gupta,Zhili Li
申请号:
US14648632
公开号:
US20150328232A1
申请日:
2013.12.02
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to pharmaceutical compositions comprising a prostacyclin, a cationic compound, and a surfactant. Particulate compositions, including liposomal, solid nanoparticulate prostacyclin compositions, including treprostinil formulations comprising cationic compound and the surfactant are also described. The present invention also relates to a system comprising the pharmaceutical composition and an inhalation device. Methods for treating pulmonary hypertension and portopulmonary hypertension with the compositions and systems described herein are also provided.